Does Formoterol Fumarate Dihydrate Interact with Nonselective Beta Adrenergic Antagonists?
Formoterol Fumarate Dihydrate and Nonselective Beta Adrenergic Antagonists have a major drug interaction according to U.S. FDA drug labeling data. May block bronchodilatory effects of formoterol and produce severe bronchospasm. Use with caution; avoid in asthma patients. The mechanism involves beta-adrenergic receptor blockade. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Major
- Formoterol Fumarate Dihydrate Class
- Corticosteroid
- Management
- Close medical supervision required
- Data Source
- U.S. FDA via OpenFDA
How This Interaction Works
The interaction between Formoterol Fumarate Dihydrate and Nonselective Beta Adrenergic Antagonists occurs because beta-adrenergic receptor blockade. Clinically, this means may block bronchodilatory effects of formoterol and produce severe bronchospasm. use with caution; avoid in asthma patients. This is classified as a major interaction, meaning it could cause serious harm if not properly managed. Your healthcare provider may need to adjust dosages, substitute one medication, or increase monitoring frequency.
What To Tell Your Doctor or Pharmacist
If you are taking Formoterol Fumarate Dihydrate and your doctor is considering prescribing Nonselective Beta Adrenergic Antagonists (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask how frequently you should be monitored while these are co-prescribed
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider