Does Aminophylline Interact with Arformoterol Tartrate?
Aminophylline and Arformoterol Tartrate have a moderate drug interaction according to U.S. FDA drug labeling data. Xanthine derivative may potentiate hypokalemia. Concomitant use may increase heart rate and systolic blood pressure. Use with caution. The mechanism involves potentiation of hypokalemic effect of beta-agonists. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Moderate
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
How This Interaction Works
The interaction between Aminophylline and Arformoterol Tartrate occurs because potentiation of hypokalemic effect of beta-agonists. Clinically, this means xanthine derivative may potentiate hypokalemia. concomitant use may increase heart rate and systolic blood pressure. use with caution. This is classified as a moderate interaction. While it may not require stopping either medication, your healthcare provider should be aware you are taking both so they can monitor for potential effects and adjust treatment if necessary.
What To Tell Your Doctor or Pharmacist
If you are taking Aminophylline and your doctor is considering prescribing Arformoterol Tartrate (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider