Nonsteroidal Anti Inflammatory Drugs Nsaids + Eplerenone Interaction

Majorinteraction on record

Description

NSAIDs may reduce antihypertensive effect and cause severe hyperkalemia in patients with impaired renal function. Monitor blood pressure and serum potassium.

Mechanism

Potassium-sparing effect combined with NSAID-related renal effects

Source: NLP:eplerenone