Nonsteroidal Anti Inflammatory Drugs Nsaids + Chlorothiazide Sodium Interaction

Moderateinteraction on record

Description

NSAIDs can reduce the diuretic, natriuretic, and antihypertensive effects of chlorothiazide sodium. Patient should be closely observed to determine if desired diuretic effect is obtained.

Mechanism

Antagonism of diuretic and antihypertensive effects

Source: NLP:chlorothiazide sodium