Nonsteroidal Anti Inflammatory Drugs (Nsaids) + Amlodipine And Benazepril Hydrochloride Interaction

Majorinteraction on record

Description

NSAIDs may result in deterioration of renal function and loss of antihypertensive effect with benazepril, especially in elderly or volume-depleted patients.

Mechanism

Reduced renal perfusion and prostaglandin inhibition

Source: NLP:amlodipine besylate and benazepril hydrochloride