Ergotamine Tartrate And Caffeine + Macrolide Antibiotics Interaction

Contraindicatedinteraction on record

Description

Contraindicated per CONTRAINDICATIONS and WARNINGS. Macrolide antibiotics elevate blood levels of ergotamine and have been reported to cause vasospastic reactions.

Mechanism

CYP 3A4 inhibition elevates ergotamine blood levels

Source: NLP:ergotamine tartrate and caffeine