Efavirenz Lamivudine And Tenofovir Disoproxil Fumarate + Phenobarbital Interaction

Moderateinteraction on record

Description

Induction of CYP3A activity by phenobarbital may increase clearance of efavirenz resulting in lowered plasma concentrations.

Mechanism

CYP3A induction

Source: NLP:efavirenz, lamivudine and tenofovir disoproxil fumarate