Amiloride Hydrochloride And Hydrochlorothiazide + Lithium Interaction

Majorinteraction on record

Description

Generally should not be given with diuretics. Diuretic agents reduce the renal clearance of lithium and add a high risk of lithium toxicity.

Mechanism

Reduced renal clearance of lithium

Source: NLP:amiloride hydrochloride and hydrochlorothiazide