Dicumarol Interactions

Allopurinol prolongs the half-life of anticoagulant dicumarol.

Source: NLP:allopurinol

Heparin may prolong prothrombin time; at least 5 hours after IV or 24 hours after SC heparin dose should elapse before blood draw for valid PT.

Source: NLP:heparin sodium in sodium chloride

Phenobarbital lowers plasma levels of dicumarol and decreases anticoagulant activity. Induction of hepatic microsomal enzymes increases metabolism and reduces anticoagulant response.

Source: NLP:phenobarbital

Phenobarbital lowers plasma levels of dicumarol and decreases anticoagulant activity. Barbiturates induce hepatic microsomal enzymes resulting in increased metabolism and decreased anticoagulant response.

Source: NLP:phenobarbital sodium

Barbiturates lower plasma levels and decrease anticoagulant activity. Dosage adjustments may be needed when barbiturates are added or withdrawn.

Source: NLP:pentobarbital sodium