Warfarin + Pantoprazole Sodium In 09 Sodium Chloride Interaction

Majorinteraction on record

Description

Increased INR and prothrombin time in patients receiving pantoprazole and warfarin concomitantly, which may lead to abnormal bleeding and death.

Mechanism

PPIs increase INR and prothrombin time

Source: NLP:pantoprazole sodium in 0.9% sodium chloride