Valproic Acid + Sodium Phenylacetate And Sodium Benzoate Interaction
Majorinteraction on record
Description
May exacerbate urea cycle disorder and antagonize efficacy by inhibiting N-acetylglutamate synthesis, a cofactor for carbamyl phosphate synthetase.
Mechanism
Inhibition of N-acetylglutamate synthesis
Source: NLP:sodium phenylacetate and sodium benzoate