Trimipramine Maleate + Fluoxetine Interaction
Moderateinteraction on record
Description
Fluoxetine inhibits P450 2D6 and increases trimipramine maleate concentrations. Caution is indicated in co-administration. Sufficient time must elapse before initiating trimipramine in patients withdrawn from fluoxetine.
Mechanism
Inhibition of cytochrome P450 2D6
Source: NLP:trimipramine maleate