Trandolapril And Verapamil Hydrochloride + Lithium Interaction
Majorinteraction on record
Description
Increased lithium neurotoxicity and serum levels reported with verapamil component. ACE inhibitor component also increases toxicity risk. Frequent monitoring recommended.
Mechanism
Reduced lithium clearance; additive effects from both components
Source: NLP:trandolapril and verapamil hydrochloride