Toremifene + Sugammadex Interaction

Moderateinteraction on record

Description

Concomitant use can delay recovery to TOF ratio of 0.9 due to displacement of vecuronium or rocuronium from the sugammadex complex.

Mechanism

High binding affinity of toremifene for sugammadex may displace neuromuscular blocking agents from the complex.

Source: NLP:sugammadex