Topotecan + Tedizolid Phosphate Interaction
Moderateinteraction on record
Description
Tedizolid inhibits BCRP, increasing plasma concentrations of orally administered topotecan. Monitor for adverse reactions; consider interrupting topotecan during tedizolid treatment due to narrow therapeutic index.
Mechanism
BCRP inhibition in the intestine
Source: NLP:tedizolid phosphate