Tiotropium Bromide And Olodaterol + Nonselective Beta Adrenergic Antagonists Interaction
Majorinteraction on record
Description
Beta-blockers may decrease effectiveness of olodaterol and produce severe bronchospasm in COPD patients. Use with caution and only when medically necessary.
Mechanism
Interference with beta-agonist effects; blockade of therapeutic action
Source: NLP:tiotropium bromide and olodaterol