Thioridazine Hydrochloride + Paroxetine Interaction
Contraindicatedinteraction on record
Description
Inhibits CYP450 2D6, elevating thioridazine levels and augmenting QTc prolongation, risking serious cardiac arrhythmias including Torsades de pointes.
Mechanism
CYP450 2D6 inhibition
Source: NLP:thioridazine hydrochloride