Theophylline + Erythromycin Ethylsuccinate Interaction
Majorinteraction on record
Description
Erythromycin may increase serum theophylline levels, potentially causing toxicity. Theophylline may decrease erythromycin concentrations by ~35%, resulting in subtherapeutic erythromycin levels.
Mechanism
Unknown mechanism for decreased erythromycin concentrations; theophylline toxicity likely due to CYP3A inhibition
Source: NLP:erythromycin ethylsuccinate