Tezacaftor And Ivacaftor + Rifampin Interaction

Majorinteraction on record

Description

Strong CYP3A inducer. Significantly decreased ivacaftor exposure by 89%; co-administration not recommended due to reduced SYMDEKO efficacy.

Mechanism

CYP3A induction

Source: NLP:tezacaftor and ivacaftor

Related drug profiles

All Tezacaftor And Ivacaftor interactions →All Rifampin interactions →
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