Tetracycline + Trastuzumab Interaction
Majorinteraction on record
Description
Patients receiving anthracyclines after stopping trastuzumab may be at increased risk of cardiac dysfunction due to trastuzumab's long washout period. Avoid anthracycline-based therapy for up to 7 months after stopping trastuzumab if possible.
Mechanism
Trastuzumab's long washout period increases cardiac dysfunction risk when combined with anthracyclines
Source: NLP:trastuzumab