Tacrolimus Extended Release Capsules + Mycophenilic Acid Interaction

Moderateinteraction on record

Description

MPA exposure is higher with tacrolimus extended-release capsules than with cyclosporine. Monitor for MPA-associated adverse reactions and reduce MPA dose as needed.

Mechanism

Tacrolimus does not interrupt enterohepatic recirculation of MPA, unlike cyclosporine

Source: NLP:tacrolimus extended-release capsules