Sulopenem Etzadroxil And Probenecid + Methotrexate Interaction
Moderateinteraction on record
Description
Probenecid inhibits OAT1/3, increasing methotrexate plasma concentrations. Monitor frequently for adverse reactions if concomitant use cannot be avoided.
Mechanism
Inhibition of organic anion transporters 1 and 3 (OAT1/3)
Source: NLP:sulopenem etzadroxil and probenecid