Sulfamethoxazole And Trimethoprim + Phenytoin Interaction

Majorinteraction on record

Description

BACTRIM inhibits hepatic metabolism of phenytoin, increasing phenytoin half-life by 39% and decreasing clearance by 27%.

Mechanism

CYP2C9 inhibition

Source: NLP:sulfamethoxazole and trimethoprim

Related drug profiles

All Sulfamethoxazole And Trimethoprim interactions →All Phenytoin interactions →
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