Sulfamethoxazole And Trimethoprim + Dapsone Gel 5 Interaction
Moderateinteraction on record
Description
TMP/SMX increases systemic levels of dapsone and its metabolites by approximately 40% for dapsone, 20% for N-acetyl-dapsone, and more than doubles dapsone hydroxylamine exposure.
Mechanism
Inhibition of dapsone metabolism
Source: NLP:dapsone gel, 5%