Sucralfate + Warfarin Interaction
Moderateinteraction on record
Description
Subtherapeutic prothrombin times reported with concomitant warfarin and sucralfate; however, clinical studies showed no change in warfarin concentration or prothrombin time. Monitor prothrombin time appropriately.
Mechanism
Sucralfate binding to warfarin in the gastrointestinal tract
Source: NLP:sucralfate oral