Spironolactone And Hydrochlorothiazide + Lithium Interaction
Contraindicatedinteraction on record
Description
Diuretics reduce renal clearance of lithium and add high risk of lithium toxicity. Lithium generally should not be given with diuretics.
Mechanism
Reduced renal clearance of lithium
Source: NLP:spironolactone and hydrochlorothiazide