Spironolactone And Hydrochlorothiazide + Indomethacin Interaction

Majorinteraction on record

Description

Combination with potassium-sparing diuretics has been associated with severe hyperkalemia; may reduce diuretic effects.

Mechanism

Hyperkalemia risk and reduced diuretic efficacy

Source: NLP:spironolactone and hydrochlorothiazide

Related drug profiles

All Spironolactone And Hydrochlorothiazide interactions →All Indomethacin interactions →
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