Sofosbuvir + St Johns Wort Interaction

Moderateinteraction on record

Description

P-gp inducer that may decrease sofosbuvir plasma concentration, leading to reduced therapeutic effect. Concomitant use not recommended.

Mechanism

P-gp induction in intestine decreases sofosbuvir plasma concentration

Source: NLP:sofosbuvir

Related drug profiles

All Sofosbuvir interactions →All St Johns Wort interactions →
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