Sodium Oxybate + Divalproex Sodium Interaction
Majorinteraction on record
Description
Concomitant use increases systemic exposure to GHB, causing greater impairment on tests of attention and working memory. An initial dose reduction of at least 20% is recommended.
Mechanism
Increases systemic exposure to GHB (sodium oxybate's active metabolite)
Source: NLP:sodium oxybate