Salicylates Greater Than 2 Gday + Levothyroxine Sodium Interaction

Moderateinteraction on record

Description

Inhibit binding of T4 and T3 to thyroxine-binding globulin, causing initial increase in FT4 followed by return to normal levels with total T4 potentially decreased by 30%.

Mechanism

Inhibition of T4 and T3 binding to thyroxine-binding globulin and transthyretin

Source: NLP:levothyroxine sodium