Relugolix%2C Estradiol Hemihydrate%2C And Norethindrone Acetate + Strong Cyp3a4 And P Glycoprotein Inducers Interaction

Majorinteraction on record

Description

Decreases AUC and Cmax of relugolix, estradiol, and/or norethindrone, may decrease therapeutic effects of MYFEMBREE. Avoid use.

Mechanism

P-glycoprotein and CYP3A induction

Source: NLP:relugolix, estradiol hemihydrate, and norethindrone acetate