Propafenone + Bupropion Hcl Er Xl Interaction
Moderateinteraction on record
Description
CYP2D6 substrate Type 1C antiarrhythmic. Bupropion inhibits CYP2D6, increasing propafenone exposure. Dose reduction may be necessary.
Mechanism
CYP2D6 inhibition
Source: NLP:bupropion hcl er (xl)