Pozelimab + Intravenous Immunoglobulin Ivig Interaction
Majorinteraction on record
Description
Intravenous immunoglobulin may decrease pozelimab concentrations by interfering with FcRn recycling mechanism. Avoid concomitant use; if unavoidable, monitor for worsening clinical signs and symptoms.
Mechanism
Interference with endosomal neonatal Fc receptor (FcRn) recycling mechanism of monoclonal antibodies
Source: NLP:pozelimab