Piperacillin And Tazobactam + Probenecid Interaction
Contraindicatedinteraction on record
Description
Probenecid prolongs half-lives of piperacillin by 21% and tazobactam by 71%. Should not be co-administered unless benefit outweighs risk.
Mechanism
Probenecid inhibits tubular renal secretion of piperacillin and tazobactam
Source: NLP:piperacillin sodium and tazobactam sodium