Phenoxybenzamine Hydrochloride + Epinephrine Interaction

Majorinteraction on record

Description

May produce exaggerated hypotensive response and tachycardia due to alpha- and beta-adrenergic receptor stimulation.

Mechanism

Phenoxybenzamine blocks alpha-adrenergic receptors, allowing unopposed beta-adrenergic effects of epinephrine

Source: NLP:phenoxybenzamine hydrochloride