Olmesartan Medoxomil Amlodipine Besylate Hydrochlorothiazide + Hydrochlorothiazide Interaction
Moderateinteraction on record
Description
Increased amlodipine exposure when coadministered with CYP3A inhibitors Hydrochlorothiazide ( 7.3 ): Antidiabetic drugs: Dosage adjustment of antidiabetic may be required. Closely monitor blood pressure, renal function and electrolytes in patients on olmesartan medoxomil, amlodipine and hydrochlorothiazide and other agents that affect the RAS. Do not co-administer aliskiren with olmesartan medoxomil, amlodipine and hydrochlorothiazide in patients with diabetes [See Contraindications (4) ].
Source: FDA drug label - olmesartan medoxomil / amlodipine besylate / hydrochlorothiazide