Olanzapine And Samidorphan L Malate + Mao Inhibitors Interaction
Moderateinteraction on record
Description
Concomitant use increases olanzapine AUC and Cmax, which may increase the risk of LYBALVI adverse reactions. Consider reducing the dosage of olanzapine component.
Mechanism
CYP1A2-mediated inhibition increasing olanzapine exposure
Source: NLP:olanzapine and samidorphan l-malate