Nsaids + Olmesartan Medoxomil And Amlodipine Besylate And Hydrochloro Interaction
Majorinteraction on record
Description
May lead to increased risk of renal impairment, loss of antihypertensive effect, and deterioration of renal function including possible acute renal failure in elderly or volume-depleted patients.
Mechanism
NSAIDs reduce antihypertensive effect and impair renal function when combined with angiotensin II receptor antagonists
Source: NLP:olmesartan medoxomil and amlodipine besylate and hydrochlorothiazide