Nsaids + Candesartan Cilexetil And Hydrochlorothiazide Interaction

Majorinteraction on record

Description

NSAIDs may result in deterioration of renal function including possible acute renal failure, especially in elderly, volume-depleted, or renally impaired patients. NSAIDs may also attenuate the antihypertensive effect.

Mechanism

Renal function impairment; attenuation of antihypertensive effect

Source: NLP:candesartan cilexetil and hydrochlorothiazide