Norethindrone Acetateethinyl Estradiol + Lamotrigine Interaction

Majorinteraction on record

Description

Hormonal products significantly decrease plasma concentration of lamotrigine, likely reducing seizure control; dosage adjustments of lamotrigine may be necessary.

Mechanism

Induction of lamotrigine glucuronidation

Source: NLP:norethindrone acetate and ethinyl estradiol