Nitrofurantoin Monohydratemacrocrystals + Probenecid Interaction
Majorinteraction on record
Description
Inhibits renal tubular secretion of nitrofurantoin, increasing serum levels and toxicity risk while decreasing urinary levels and efficacy as urinary tract antibacterial.
Mechanism
Inhibition of renal tubular secretion
Source: NLP:nitrofurantoin (monohydrate/macrocrystals)