Netupitant And Palonosetron + Dexamethasone Interaction

Moderateinteraction on record

Description

Netupitant increases systemic exposure of dexamethasone more than 2-fold on Days 2 and 4; administer reduced dose of dexamethasone with AKYNZEO.

Mechanism

CYP3A4 inhibition by netupitant

Source: NLP:netupitant and palonosetron