Naltrexone Hydrochloride And Bupropion Hydrochloride + Opioid Analgesics Interaction

Moderateinteraction on record

Description

Patients may not fully benefit from opioid-containing medicines. CONTRAVE therapy should be temporarily discontinued for intermittent opiate treatment. May be used with caution after chronic opioid use stopped for 7-10 days to prevent withdrawal precipitation.

Mechanism

Naltrexone antagonism of opioid effects

Source: NLP:naltrexone hydrochloride and bupropion hydrochloride