Moxifloxacin Hydrochloride Tablets 400 Mg + Didanosine Interaction
Moderateinteraction on record
Description
Buffered didanosine tablets contain divalent and trivalent cations that form chelates with moxifloxacin, substantially decreasing moxifloxacin absorption. Separate dosing by at least 4 hours before or 8 hours after.
Mechanism
Chelation with multivalent cations reduces drug absorption
Source: NLP:moxifloxacin hydrochloride tablets, 400 mg