Monoamine Oxidase Inhibitors Maois + Metoprolol Succinate Er Interaction

Majorinteraction on record

Description

Catecholamine depleting drugs with additive effect when given with metoprolol succinate ER, may cause hypotension or marked bradycardia with vertigo, syncope, or postural hypotension.

Mechanism

Additive catecholamine depletion effect

Source: NLP:metoprolol succinate er