Monoamine Oxidase Inhibitors Maois + Brompheniramine Maleate Pseudoephedrine Hydrochloride And De Interaction

Contraindicatedinteraction on record

Description

Hyperpyrexia, hypotension, and death reported with coadministration. MAO inhibitors prolong/intensify anticholinergic effects and enhance pseudoephedrine effect.

Mechanism

MAO inhibitor interaction with dextromethorphan; potentiation of anticholinergic and sympathomimetic effects

Source: NLP:brompheniramine maleate, pseudoephedrine hydrochloride and dextromethorphan hydrobromide