Moderate To Strong Cyp2c19 Inducers + Mavacamten Interaction

Contraindicatedinteraction on record

Description

Concomitant use decreases mavacamten exposure and may reduce efficacy. Risk of heart failure may increase upon discontinuation. Contraindicated.

Mechanism

CYP2C19 induction decreases mavacamten plasma concentrations

Source: NLP:mavacamten