Metoprolol Tartrate And Hydrochlorothiazide + Epinephrine Interaction
Majorinteraction on record
Description
Patients taking metoprolol with history of severe anaphylactic reactions may be unresponsive to usual doses of epinephrine used to treat allergic reactions.
Mechanism
Beta blockade reduces responsiveness to epinephrine
Source: NLP:metoprolol tartrate and hydrochlorothiazide