Methotrexate + Daunorubicin Hydrochloride Interaction
Moderateinteraction on record
Description
High-dose methotrexate is hepatotoxic and may impair liver function, increasing risk of daunorubicin toxicity. Dosage reduction may be required.
Mechanism
Hepatotoxicity impairing liver function and drug clearance
Source: NLP:daunorubicin hydrochloride