Methenamine Sodium Phosphate Monobasic Monohydrate Phenyl Sa + Ketoconazole Interaction

Moderateinteraction on record

Description

May cause increased gastrointestinal pH resulting in marked reduction in ketoconazole absorption. Take combination at least 2 hours after ketoconazole.

Mechanism

Increased gastrointestinal pH reducing ketoconazole absorption

Source: NLP:methenamine, sodium phosphate, monobasic, anhydrous, phenyl salicylate, methylene blue and hyoscyamine sulfate